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Lead can reach the levels of 2,700 times higher in acanthocephalans ( Pomphorhynchus laevis ) than in the muscle of its fish host, the European chub ( Squalius cephalus , Thielen et al., 2004), in a wide range of parasite species (acanthocephalans, cestodes, nematodes, and digeneans, Littorina littorea) ( Perca fluviatilis) , and eels ( Anguilla anguilla) ( Carcharhinus dussumieri) ( Amietophrynus regularis , Phalacrocorax carbo , Phocoena , In situ observations, as well as experimental exposure studies ( Similar findings have been reported for organic pollutants (mainly persistent ones), but studies remain scarce because of analytical challenges in providing accurate methods to quantify chemical analytes, such as their metabolites, from a limited amount of biological samples